NIEHS Comparative Mouse Genomics Centers Consortium (CMGCC)

Welcome to the Cincinnati Comparative Mouse Genomics Centers Consortium Website

People

Personnel Contact ID Department Organization
Peter J. Stambrook, Ph.D. Peter.Stambrook@uc.edu Cell Biology University of Cincinnati
Yolanda Sanchez, Ph.D. Yolanda.Sanchez@uc.edu Biochemistry & Molecular Genetics University of Cincinnati
Erik Knudsen, Ph.D. Erik.Knudsen@uc.edu Cell Biology University of Cincinnati
Tom Doetschman, Ph.D Tom.Doetschman@uc.edu Biochemistry & Molecular Genetics University of Cincinnati
Bruce Aronow, Ph.D Bruce.Aronow@chmcc.org Pediatric Informatics Molecular Dev Biol University of Cincinnati/CCHMC

Projects

Projects Lab Model System/Source Stage
PLK3 Stambrook Mice models with SNPs in Plk3 CITB Mouse 129 BAC library from Research Genetics In Progress
CHEK1 Sanchez Hypomorphic alleles (Yeast/Mouse: deletion and point mutants) Cre/Lox and FLP/FRT In Progress
RB & CCND1 Knudsen Cyclin D1 aberrant splice mouse models

Low penetrance alleles of RB

Mice models with differing alleles of p16ink4a

 Collaboration with MD Anderson group, Smithville Texas

R6661W murine equivalent & ES cells

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 In Progress
Bioinformatics Aronow GeneServer, SNP-Protein structure mapper, Trafac, Pathways, Expression Database - In Progress

Cincinnati Genes:

The CMGCC Mission:

Are there functional consequences of polymorphisms in the human genes for DNA damage repair and cell-cycle control genes?

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11/29/2002